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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d988cc6a8f0eba425f347579273bb600f9aa1215d3d75a543e6b63dbe8a53a5' 
  AND token = 'CFgBAT4WSbPMJMieaq0GwTqizkR8R+spd72SSjWy8Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}