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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165b073cadc03fd1103b3e6b8eae0358ee2e2ee591ef52b28ac697ce79a61f6f' 
  AND token = 'u3LHxzNBIgI6+EL7Pdi9WcFKSzRvJcs1oU5JeyWwBmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}