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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c918a935a0e8316d7bb8ec8562dd240eb6625b78462ee2796d89543a925999b4' 
  AND token = 'M/Y3h2zC8L5VpElTR6AJCaQjOEM+WuyKg0INQ5B61Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}