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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '021d971d29084033d53d015fc6019d0593637a5140c5bdd650d209379fab1f9f' 
  AND token = 'QvJqakQFJK7fM8KQ2VG52ghRoDmbE9iX7JfDilCJ+M4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}