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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1591ddec2e2f2ace113db906c72bd3eeb8cfbe2dbfd81eda8e196ec116a3456b' 
  AND token = '+OAIjmzn3u2y8QIaSIyumq2borr6NEH2L8C5SczajeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}