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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c48d4ce583faec1e744ed253474cb8ec559750e6b580e8e1c65b1151e2b978c8' 
  AND token = 't7wRx/wnkn8/+VTyJq9wu69OKKOEaCcCG1mkLc9rB04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}