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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7153bf67f3d59865cd1adaf583cda0d28280082ff575c1f91bb51b5005e97208' 
  AND token = 'iVHHa4lvCJdhm1LNwraXto180BCGWvMvkoj1gQJTBe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}