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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d4a66a559b607c3d1d387d76c0a47f27ec6038c7ccdf918a2edd163fa6d050a' 
  AND token = 'oTZ49MrTiMtwYkYN4dGEyaq3ouEY4zcj9MJSv3Een7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}