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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '516138f4c903d85d9ed5945f777251e03bb6deeed7ef42f87e51486810ad89c0' 
  AND token = 'z+DG70hzi2IyXnGXTlmwwdkoqu3VPXED8n4SCCyuEn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}