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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99e562cc29b72003e89ef45415f532652897d5ea6b1b7b42a792b53914b13f69' 
  AND token = 'hkLaStz0sx7V32i6iK3uM4cMAFcucyzgOSVaYUjzgW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}