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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46be223b27476662bb25b0c968856141fdad69a72a9b0570c0ebde4d2b71ee1a' 
  AND token = 'Qq3S+7/VxoPddFXqZSbG1bNZConenCwXqGNW6oR2Hmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}