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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aa22355dffaa841a507a4b7b2c379d3a9d0c857f227b0472080b9ab9af9079a' 
  AND token = 'rpkQAqG68ai+maFUj66Rbxk74qoPx/MKw6VI29A3noU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}