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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c5b2895a0e55cdd4ab287e9b9ffcf5e7c018a60f260f11b318c5f6792633259' 
  AND token = 'Bu+5F0vzHrE5sYtc+cDUYuLKkEyZKnhr29wwJbPaxHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}