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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f80ed61a70dd961f5c4fee8b3d725039093919a8728b904a96ebbf64035464d' 
  AND token = 'N5/LMkieR1SyRCQZ+ecvn6toKWFRjICQVAM0jXG4stU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}