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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45690fead67d2f352a8ea5346bfcf9ae84a1343a81fff06613dbe884d14df185' 
  AND token = 'VkiYnVMy5xz3Vp8ZDiuHpVnR9WK1SiK92ZmJ0UQTAj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}