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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb941afec571f944da612989f73a7ecfada1630f73d7992d0fa13b51fdcbe3c7' 
  AND token = 'lWI1CT6lSnTs2i744IGcxzG+pb/3I7B2M5IcY5mKoe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}