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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6149ac798ed0380cfc84940cfd9af757dd1ea3454cb7a806403794bec8e8170' 
  AND token = 'XHZwSFdGszQwbFiiSMTw58iNT/w4vY+fwUoTegm+VmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}