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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '043557079488ff8ad15da67c8f6e900a83f0c71db31fd6be02eb5abefd918834' 
  AND token = 'qUjJQ9CWqWcdcgHiFHNJAMnDU89EiT4Ir6SyQfnhmeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}