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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35171d1733060e4674c9e53cb0cd85e795f6a6d8df15118aa37f07c1499bb919' 
  AND token = 'N9hk2bS8SvUHUy4/TfrJNO9/NHrFRTE+P5dF5OMR6js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}