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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d6147f355831b3f9cd963046c3814b05d271f6335b284d88d030ce30c0dc07' 
  AND token = 'UbuHg5LLd2h8QN0N48xV60flXSkJcaTNslKpEQg6z0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}