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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13c01f812925839518d3a41182336ab78aaa06efd1a365aef9d34062dcaf7037' 
  AND token = 'FvDSntSNcAV2yxQDlYdsPjH43usZgAUZresA8LrVlAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}