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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '351ee2f428adf78c1ba5fce8c05a1a541b2c3c7b019d65fce8acf87e700b0d54' 
  AND token = 'cjmA5nqTIu0QMXE7oz0LtB+JDSOqzpLbICkTGIRsv54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}