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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e40ae6c3969c32f2c0fee77a57bc8ad6f97c25d51738318085642f4e153b5dc' 
  AND token = 'RcifH8KQI44RjaSAdL4XLGMkxtJ8PbZ+a54YF32qRgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}