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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a273f2391fb6b0a9c235f56ba1765b9fd206fdec13be862bb7a3bfd65f0de01c' 
  AND token = 'ips1yyyEev1VE9Uhm8h9NawVn96Jge4l1qQ/n/cZTKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}