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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e90ab06ccaf99fbce4a041c67217c6d4a4b642b0ce8b593f4a0bbf808a6d3c2' 
  AND token = 'vkf0TTDLFUCMq/At6Fr3Pqgov/KX70kbWY+JbB5B+dY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}