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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dce7d238c48666a4cf4e672e20015d52729b24e2081a13307ad34251328f448' 
  AND token = 'Za2G3DLYpVufBq9lHVp1Rhpeplca96Zfw9MUeUS6oFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}