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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12e1f611b24e3f1c37670250d96b26a1ef19bb2c541e3523f55596ff59a4bc1e' 
  AND token = '2KCeSiFD6ssZ/e8Xmvl0VoaCGQhPDpw5ugV2RWTcg88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}