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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2efb62a5d1fb596baef3b19ee1dafc7a3eb708161e2e563b2f62587e2c64e003' 
  AND token = 'QlyRQSmMQWbYoqoBGuuobR8Z1kArtpYn1p3MdVkoHkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}