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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c44dda9907bd0a70b9d676c888d673f059709f2a4a60a17c44b553137ce316' 
  AND token = 'eYa3qxXlxPta32shgFumTnrx/K7NDdIbL6rhflRD3Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}