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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd478b3b5bd4bd12dca301c3af3965c8d32e68e0c7f4dc1fd43ece966ed582029' 
  AND token = 'fMkoHOMMhyIXjXTzB+MWe8MHSvpGdsijabm1D01jnaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}