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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce03861f0bba6c896367ee5860b31784d09aac0116be1a1579e56187a4330aa' 
  AND token = 'jT+B60tIDfXVOUyPTK09bqQMCNy7mz5GFkc4fy77ITA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}