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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d348eb138cec7dabd1e39e43a9e08ce61cbf9e7b10634bb3f97f83934c0dd6d' 
  AND token = '5LeIx5Rlr93QILI0lcuYVXnwG+F3H+Y+6XioYn4kh9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}