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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a5d33ad6a343578496a8be6052543fd3c5fde4c13b4b1ae363eeefd02fff379' 
  AND token = '/k/PucUfkI0tItIqepfkIgBPUltFCb3pKKAjdVCwYsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}