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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adf49b63cb711efeef3cc3c0f2ef804abdc80c32d88d30147e0a8c18245eeb50' 
  AND token = 'buVk09CtxPVumNz3Pq+mJkxgwmzrMqel8WPntp1DO7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}