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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd296cfdf3436f2b7c3910d01b01d1c21e2344939edc7bee01abe69b7f4e2e6c7' 
  AND token = 'I7Vb8jPCptjUvvRQ6m71hPUSE7ubwS3iJJESLQ5bxPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}