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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '121237e216cb04940d793e652e0252eeea9f725e3320c922ab8f17c421d4b6cc' 
  AND token = 'MpEe9gcGlRXLxpA8J1NMjTmsaOXpzpoSjyrcHifo0m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}