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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd3ce898699ae41e18a1863aeafd1f49e05f118c9e4b02f523028e45f32e41ab' 
  AND token = 'WuKHIUy7j2hQn2wTEDHycffyklfvy6zAInCtBIq9PPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}