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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62256f1c1af633e5bfb5faa7cb92988e08be885f4ab3f8b7dac23839b4ede606' 
  AND token = '3EhL22eCUAtK5XhN6gC8ViaHcZslQ38GQ/tpsI9HoP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}