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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db8e14d834e0a0ebf35a3914b1fbf041d3d843652f32b3545f1d9da3ce2722c' 
  AND token = 'VPoJjdvFXCRdixNpqooryrvpgx2m8pMbmT5j868VyLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}