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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c3d67a7daae384e79aa42b7c04477a3f645feccc2a9da531b03f23f943fb13f' 
  AND token = 'QNDORliH7JIJpC4O0VYZx3mCKMVnn+9zWems7669TH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}