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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b0b356a308b4988bdf3c0fdb449024aeb27834a8fd7fd93c3ec6571ec69b411' 
  AND token = 'lfO/7e+3D6Q+fY/77QXL4neCgzHf4tSsosxNMyvFuH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}