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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e062f43d841c1c41b90028d455c691b1fb618343c91ae31cd79f272be515a486' 
  AND token = 'yZs1jzE72j7TxNF4ImS/l1JUyTeWcYnx+L1d0rYCSHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}