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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d269827af66f68c0fd4619fdeca918afa56f56843af8738cf905a01a0c2274' 
  AND token = 'QlU3ACL0OlYYB68lMWI6xeYABpYsZyjkCbGE8SCCtHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}