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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ad3efcc375734237f534f1f7659bf1a10e19ba07ef264bb44754aa6d1b89c73' 
  AND token = '2QxxVFpgP4pzz195OUKtpfH3wzzyf34LID3FmaCkNVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}