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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb659eeb713a6c773a7fc1f6b44668b738d58ee9752f5a533a8e95cd5b6f31b3' 
  AND token = 'CjgYGAg2DGPjpV4U68pm16cNfdFV9iYbRJ7hYWSLqDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}