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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79e8a8aed3a1d9565bbb00e27ca80f8e8b1b3b433beed03f6495af686c98d6fc' 
  AND token = 'eV01Jn05k4meo+PmVELDRyztSTjt4fPQFyIgniaQyY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}