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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cdf5e3506fadccac446140fdf16b33fbdd0991a60b292503dd1b963670c8f26' 
  AND token = 'weOPjsbkj6mqznoX/6Y5INDozygjHjdVPSwUNJLdqk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}