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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88c78bf1911448c57fffa4381c98b6f4531b83bbd6ab0fe8aed972eed148ca6' 
  AND token = 'am5RTYe4yEnXefAAbo0byIp1pf3hDzzz0NNFfsIe/Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}