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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d33e7819cf0230382203e8ce1d40b17a14aad50302c4e5a2f3268c5db7b29fb' 
  AND token = 'xC1eLax1eCfTZtjG/9K4Gyl08mZvZrccDahHBkav0P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}