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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0829f4f3afa235c782897b26ddabec1f0286e55c916a90ec03d690f45b56e43' 
  AND token = 'JjVNwDDOH4OLyCGNWCA7+cehKHaOPGQjlc1pAMWVacQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}